Literature - The Science behind the Facts

At the core of our company is a commitment to research and development. Every report, article, and product we create is based on the expertise of our in-house scientific team. From diagnostics to educational materials, we rely on peer-reviewed studies, clinical guidelines, and the latest advancements in allergy, food intolerance and autoimmune research.

This page provides a comprehensive list of the references that are used for our content, offering transparency and enabling you to explore the origins of the information we share

Gluten Related Disorders

General Information

Catassi, C., Bai, J. C., Bonaz, B., et al. (2013). Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related Disorders. Nutrients, 5(10), 3839–3853.
Sapone, A., Lammers, K. M., Mazzarella, G., et al. (2011). Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity. BMC Medicine, 9, Article 23.
Schuppan, D., & Zimmer, K. P. (2013). The diagnosis and treatment of celiac disease. Deutsches Ärzteblatt International, 110(49), 835–846.
Reilly, N. R., & Green, P. H. R. (2012). Epidemiology and clinical presentations of celiac disease. Seminars in Immunopathology, 34(4), 473–478.

Tissue Transglutaminase (tTG)

Hill, I. D., Dirks, M. H., Liptak, G. S., et al. (2017). Guideline for the diagnosis and treatment of celiac disease in children: Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Journal of Pediatric Gastroenterology and Nutrition, 45(4), 495–505.
Esposito, C., Paparo, F., Caputo, I., et al. (2003). Expression and enzymatic activity of small intestinal tissue transglutaminase in celiac disease. American Journal of Gastroenterology, 98, 1813–1820.
Kagnoff, M. F. (2005). Overview and pathogenesis of celiac disease. Gastroenterology, 128, S10–S18.

tTG neo-epitopes (tTG neo)

Sugai, E., Moreno, M. L., Hwang, H. J., et al. (2010). Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable in select cases? World Journal of Gastroenterology, 16(25), 3144–3152.
Matthias, T., Neidhöfer, S., Jeremias, P., & Lerner, A. (2016). New markers for celiac disease: Anti-Neo-Epitope Human and Microbial Transglutaminases [abstract]. Arthritis Rheumatology, 68(suppl 10).
Bizzaro, N., Villalta, D., Tonutti, E., et al. (2012). Sensitivity specificity of a novel ELISA for celiac disease antibodies using human recombinant tissue transglutaminase deamidated gliadin peptides as antigen. Clinica Chimica Acta, 413(7–8), 877–882.
Lerner, A., Jeremias, P., & Matthias, T. (2016). Antibodies against neo-epitope of microbial and human transglutaminase complexes as biomarkers of childhood celiac disease. Journal of Immunological Methods, 429, 15–20.
Agardh, D., Matthias, T., Wusterhausen, P., et al. (2020). Antibodies against neo-epitope of microbial and human transglutaminase complexes as biomarkers of childhood celiac disease. Clinical and Experimental Immunology, 199(3), 294–302.
Matthias, T., Neidhöfer, S., Pfeiffer, S., et al. (2011). Novel trends in celiac disease. Cellular & Molecular Immunology, 8(2), 121–125.
Mylek, D., Tighe, P., & Spencer, J. (2018). The diagnostic utility of neo-epitope based ELISA assays for coeliac disease: A systematic review and meta-analysis. BMC Gastroenterology, 18, Article 133.

Microbial Transglutaminase (mTG)

Lorand, L., & Graham, R. M. (2003). Transglutaminases: Crosslinking enzymes with pleotropic functions. Nature Reviews Molecular Cell Biology, 4(2), 140–156.
Lerner, A., & Matthias, T. (2015). Microbial Transglutaminase is Immunogenic and Potentially Pathogenic in Pediatric Celiac Disease. Frontiers in Pediatrics, 3, Article 70.
Wieser, H., & Koehler, P. (2012). The biochemical basis of celiac disease. Cereal Chemistry, 89(3), 181–190.
Lerner, A., & Matthias, T. (2020). Food industrial microbial transglutaminase in celiac disease: Treat or trick. International Journal of Molecular Sciences, 21(3), Article 1127.
Rubio-Tapia, A., Hill, I. D., Kelly, C. P., Calderwood, A. H., & Murray, J. A. (2013). ACG Clinical Guidelines: Diagnosis and Management of Celiac Disease. American Journal of Gastroenterology, 108(5), 656–676.
Matthias, T., Jeremias, P., & Neidhöfer, S. (2016). The industrial food additive microbial transglutaminase mimics tissue transglutaminase and is immunogenic in celiac disease patients. Autoimmunity Reviews, 15(9), 759–765.

mTG neo-epitopes (mTG neo)

Lorand, L., & Graham, R. M. (2003). "Transglutaminases: Crosslinking Enzymes with Pleotropic Functions." Nature Reviews Molecular Cell Biology, 4(2), 140-156.
Lerner, A., Jeremias, P., Neidhöfer, S., & Matthias, T. (2016). „Antibodies against neo-epitope of microbial and human transglutaminase complexes as biomarkers of childhood celiac disease”. Journal of Immunological Methods, 429, 15-20.
Lerner, A., & Matthias, T. (2015). "Microbial Transglutaminase is Immunogenic and Potentially Pathogenic in Pediatric Celiac Disease." Frontiers in Pediatrics, 3, Article 70.
Lerner, A., Matthias, T. (2020). "Food industrial microbial transglutaminase in celiac disease: treat or trick." International Journal of Molecular Sciences, 21(3), 1127.
Wieser, H., & Koehler, P. (2012). "The Biochemical Basis of Celiac Disease." Cereal Chemistry, 89(3), 181-190.
Rubio-Tapia, A., Hill, I. D., Kelly, C. P., Calderwood, A. H., & Murray, J. A. (2013). "ACG Clinical Guidelines: Diagnosis and Management of Celiac Disease." The American Journal of Gastroenterology, 108(5), 656-676.
Reif, S., & Lerner, A. (2004). "Tissue Transglutaminase—The Key Player in Celiac Disease: A Review." Autoimmunity Reviews, 3(1), 40-45.
Lerner, A., Matthias, T. (2015). "Microbial transglutaminase: A new potential player in celiac disease." Clinical Reviews in Allergy & Immunology, 50(2), 117-130.
Matthias, T., Jeremias, P., Neidhöfer, S., et al. (2016). "The industrial food additive microbial transglutaminase mimics tissue transglutaminase and is immunogenic in celiac disease patients." Autoimmunity Reviews, 15(9), 759-765.
Lytton, S. D., Antiga, E., Pfeiffer, S., Matthias, T., et al. (2013). “Neo-epitope tissue transglutaminase autoantibodies as a biomarker of the gluten-sensitive skin disease—dermatitis herpetiformis”. Clinica Chimica Acta, 415, 346-349.

Deamidated Gliadin Peptides (DGP)

Fasano, A., & Catassi, C. (2012). Celiac Disease. New England Journal of Medicine, 367(25), 2419–2426.
Villalta, D., et al. (2010). Antibodies to Deamidated Gliadin Peptide in the Diagnosis of Celiac Disease: High Diagnostic Accuracy and Correlation with Intestinal Damage. Journal of Pediatric Gastroenterology and Nutrition, 60(6), 626–631.
Falini, M. L., Elli, L., Caramanico, R., et al. (2008). Immunoreactivity of antibodies against transglutaminase-deamidated gliadins in adult celiac disease. Digestive Diseases and Sciences, 53, 2697–2701.
Schuppan, D., & Zimmer, K. P. (2013). The diagnosis and treatment of celiac disease. Deutsches Ärzteblatt International, 110(49), 835–846.
Monachesi, C., Catassi, C., & Lionetti, E. (2022). Diagnostic Accuracy of IgA Anti-Transglutaminase and IgG Anti-Deamidated Gliadin for Diagnosis of Celiac Disease in Children under Two Years of Age: A Systematic Review and Meta-Analysis. Nutrients, 14(1), Article 7.
Murch, S. H., et al. (2013). Application of Deamidated Gliadin Antibodies in the Follow-Up of Treated Celiac Disease. PLOS ONE, 8(9), Article e67452.

Gliadin

Fasano, A., & Catassi, C. (2012). Celiac Disease. New England Journal of Medicine, 367, 2419–2426.
Hill, I. D., Dirks, M. H., Liptak, G. S., Colletti, R. B., Fasano, A., Guandalini, S., & Seidman, E. G. (2005). Guideline for the diagnosis and treatment of celiac disease in children: Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Journal of Pediatric Gastroenterology and Nutrition, 40(1), 1–19.
Dieterich, W., Ehnis, T., Bauer, M., Donner, P., Volta, U., Riecken, E. O., & Schuppan, D. (1997). Identification of tissue transglutaminase as the autoantigen of celiac disease. Nature Medicine, 3, 797–801.
Catassi, C., Bai, J. C., Bonaz, B., Bouma, G., Calabrò, A., Carroccio, A., & Fasano, A. (2013). Non-celiac gluten sensitivity: The new frontier of gluten related disorders. Nutrients, 5(10), 3839–3853.

Frazer’s fraction

Frazer’s fraction III detects gluten sensitivity (1990). Inpharma Weekly, 741, 20–21.
Meyer, N., Illarionov, B., Fischer, M., & Wieser, H. (2024). Preparation and Immunochemical Characterization of a Water-Soluble Gluten Peptide Fraction for Improving the Diagnosis of Celiac Disease. Nutrients, 16(5), Article 742.
Reinke, Y., Zimmer, K.-P., & Naim, H. Y. (2009). Toxic peptides in Frazer's fraction interact with the actin cytoskeleton and affect the targeting and function of intestinal proteins. Experimental Cell Research, 315(19), 3442–3452.

Transglutaminase 3 (TG3)

Paolella, G., Sposito, S., Romanelli, A. M., & Caputo, I. (2023). Type 2 Transglutaminase in Coeliac Disease: A Key Player in Pathogenesis, Diagnosis and Therapy. International Journal of Molecular Sciences, 24(4), Article 2500.
Kárpáti, S. (2013). Transglutaminases in cutaneous barrier formation and environmentally induced allergic and immunological skin diseases. Allergo Journal International, 22, 550–552.
Schuppan, D., & Dieterich, W. (2001). Epidermal Transglutaminase (TGase 3) Is the Major Autoantigen of Dermatitis Herpetiformis. Journal of Investigative Dermatology, 116(4), 618–624.
Sárdy, M., Kárpáti, S., Merkl, B., Paulsson, M., & Smyth, N. (2002). Epidermal transglutaminase is the autoantigen of dermatitis herpetiformis. Journal of Experimental Medicine, 195(6), 747–757.
Caputo, I., & Iaccarino, O. (2014). Epidermal Transglutaminase: The Key Autoantigen in Dermatitis Herpetiformis. Journal of Clinical & Cellular Immunology, 5(4).

Allergy

Pollen

Common Ragweed (w1)

Asero, R., Bellotto, E., Ghiani, A., et al. (2014). Concomitant sensitization to ragweed and mugwort pollen: Who is who in clinical allergy? Annals of Allergy, Asthma & Immunology, 113(3), 307–313.
Adams-Groom, B., Selby, K., Derrett, S., et al. (2022). Pollen season trends as markers of climate change impact: Betula, Quercus and Poaceae. Science of the Total Environment, 835, 155562.

Mugwort (w6)

Lukschal, A., Wallmann, J., Bublin, M., et al. (2016). Mimotopes for Api g 5, a relevant cross-reactive allergen, in the celery-mugwort-birch-spice syndrome. Allergy, Asthma & Immunology Research, 8(2), 124–131.
Biedermann, T., Winther, L., Till, S. J., et al. (2019). Birch pollen allergy in Europe. Allergy, 74(7), 1237–1248.
Lao-Araya, M. (2024). Novel approaches to allergen immunotherapy for respiratory allergies. Pharmaceuticals (Basel), 17(11), 1510.

Timothy Grass (g6)

Schoenwetter, W. F., Dupclay, L., Appajosyula, S., et al. (2004). Economic impact and quality-of-life burden of allergic rhinitis. Current Medical Research and Opinion, 20(3), 305–317.
Bousquet, J., et al. (2008). Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update. Allergy, 63(s86), 8–160.
D’Amato, G., Cecchi, L., Bonini, S., et al. (2007). Allergenic pollen and pollen allergy in Europe. Allergy, 62(9), 976–990.

Grass Mix (gx17)

Gangl, K., Niederberger, V., Valenta, R., et al. (2017). Marker allergens and panallergens in tree and grass pollen allergy. In Molecular Allergy Diagnostics (pp. 203–226).
Focke-Tejkl, M., Campana, R., Reininger, R., et al. (2014). Dissection of the IgE and T-cell recognition of the major group 5 grass pollen allergen Phl p 5. Journal of Allergy and Clinical Immunology, 133(3), 836–845.e11.
Swoboda, I., De Weerd, N., Bhalla, P. L., et al. (2002). Mutants of the major ryegrass pollen allergen, Lol p 5, with reduced IgE-binding capacity: Candidates for grass pollen-specific immunotherapy. European Journal of Immunology, 32(1), 270–280.
D’Amato, G., Cecchi, L., Bonini, S., et al. (2007). Allergenic pollen and pollen allergy in Europe. Allergy, 62(9), 976–990.

Rye (g12)

Aalberse, R. C. (2000). Structural biology of allergens. Journal of Allergy and Clinical Immunology, 106(2), 228–238.
D’Amato, G., Cecchi, L., Bonini, S., et al. (2007). Allergenic pollen and pollen allergy in Europe. Allergy, 62(9), 976–990.

Bermuda Grass (g2)

Matthiesen, F., Schumacher, M. J., Løwenstein, H. (1991). Characterization of the major allergen of Cynodon dactylon (Bermuda grass) pollen, Cyn d I. Journal of Allergy and Clinical Immunology, 88(5), 763-774.
Weber, R. W. (2004). Cross-reactivity of pollen allergens. Current Allergy and Asthma Reports, 4(5), 401-408.

Bahia Grass (g17)

Ghobrial, G., Naser, S. A., Sweeney, M., et al. (2002). Identification and characterization of the allergenic proteins of Bahia grass (Paspalum notatum) pollen. International Archives of Allergy and Immunology, 128(4), 304-309.
Weber, R. W. (2004). Cross-reactivity of pollen allergens. Current Allergy and Asthma Reports, 4(5), 401-408.

Olive (t9)

Kalogeromitros, D., Armenaka, M., Toumbis-Ioannou, E., et al. (2001). Allergy to olive pollen: A study of four family members. Allergy Asthma Proceedings, 22(1), 39-41.
Weber, R. W. (2007). Cross-reactivity of pollen allergens: Impact on allergen immunotherapy. Annals of Allergy, Asthma & Immunology, 99(3), 203-211.
Cases, B., et al. (2014). Immunological cross-reactivity between olive and grass pollen: Implication of major and minor allergens. World Allergy Organization Journal, 7(1), 11.

Silver Birch (t3)

Breiteneder, H., & Ebner, C. (2000). Molecular and biochemical classification of plant-derived food allergens. Journal of Allergy and Clinical Immunology, 106(1), 27–36
Eriksson, N. E., Formgren, H., & Svenonius, E. (1982). Food hypersensitivity in patients with pollen allergy. Allergy, 37(6), 437–443.

Tree Mix (tx17)

Asam, C., Hofer, H., Wolf, M., et al. (2015). "Tree pollen allergens—an update from a molecular perspective." Allergy, 70(10), 1201-1211.
Hirschwehr, R., Valenta, R., Ebner, C., et al. (1992). "Identification of common allergenic structures in hazel pollen and hazelnuts: A possible explanation for sensitivity to hazelnuts in patients allergic to tree pollen." Journal of Allergy and Clinical Immunology, 90(6 Pt 1), 927-936.
Weber, R. W. (2003). "Patterns of pollen cross-allergenicity." Current Reviews of Allergy and Clinical Immunology, 112(2), 229-239.

Tree Mix (tx21)

Weber, R. W., et al. (2007). Cross-reactivity of pollen allergens: impact on allergen immunotherapy. Annals of Allergy, Asthma & Immunology, 99(3), 203–211.
D'Amato, G., et al. (2001). Urban air pollution and plant-derived respiratory allergy. Clinical and Experimental Allergy, 30(5), 628–636.
D'Amato, G., et al. (2007). Allergenic pollen and pollen allergy in Europe. Allergy, 62(9), 976–990.
Kosisky, S. E., Marks, M. S., & Nelson, M. R. (2010). Pollen aeroallergens in the Washington, DC, metropolitan area: A 10-year volumetric survey (1998–2007). Annals of Allergy, Asthma & Immunology, 104(3), 223–235.

Japanese Hops (w22)

Piasecka-Kwiatkowska, D., et al. (2024). Allergenic Potential of Common Hops (Humulus lupulus L.) in the Context of Cross-Reactions with Pollen Allergens. Nutrients, 16(21), 3626.
Biedermann, T., Winther, L., Till, S. J., et al. (2019). Birch pollen allergy in Europe. Allergy, 74(7), 1237–1248.
Katelaris, C. H., Heinzerling, L., Winther, L., et al. (2004). Hops allergy in the brewing industry. Allergy, 59(7), 809–810.

Plant

Ficus/Latex Mix (Kx1)

Blanco, C., Carrillo, T., Castillo, R., et al. (1994). Latex allergy: Clinical features and cross-reactivity with fruits. Annals of Allergy, Asthma & Immunology, 72(4), 309–314.
Beezhold, D. H., Thompson, R. L., Sussman, G. L., et al. (1996). Latex allergy: A preventable healthcare problem. Journal of Allergy and Clinical Immunology, 97(4), 1252–1256.
Brehler, R., Theissen, U., Mohr, C., & Luger, T. (1997). Latex-fruit syndrome: Frequency of cross-reacting IgE antibodies. Allergy, 52(4), 404–410.
Brehler, R., Abrams, E., & Sedlmayr, S. (1998). Cross-reactivity between Ficus benjamina (weeping fig) and natural rubber latex. Allergy, 53(4), 402–406.

Blomia tropicalis (d201)

Juliá-Serdá, G., Cabrera-Navarro, P., Acosta-Fernández, O., et al. (2012). Prevalence of sensitization to Blomia tropicalis among young adults in a temperate climate. Journal of Asthma, 49(4), 349-354.
Tsai, J. J., Cheng, F. C., Chua, K. Y., et al. (2003). Identification of the major allergenic components in Blomia tropicalis and the relevance of the specific IgE in asthmatic patients. Annals of Allergy, Asthma & Immunology, 91(5), 485-489.
Arruda, L. K., Vailes, L. D., Platts-Mills, T. A., et al. (1997). Sensitization to Blomia tropicalis in patients with asthma and identification of allergen Blo t 5. American Journal of Respiratory and Critical Care Medicine, 155(1), 343-350.

Pet Dander

Cat Dander (e1)

Custovic, A., et al. (1998). Distribution, aerodynamic characteristics, and removal of the major cat allergen Fel d 1 in British homes. Thorax, 53(1), 33–38.
Woodfolk, J. A., et al. (1997). Evaluation of different techniques for washing cats: Quantitation of allergen removed from the cat and the effect on airborne Fel d 1. Journal of Allergy and Clinical Immunology, 100(3), 307–312.
Bonnet, B., Messaoudi, K., Jacomet, F., et al. (2018). An update on molecular cat allergens: Fel d 1 and what else? Chapter 1: Fel d 1, the major cat allergen. Allergy, Asthma & Clinical Immunology, 14, 14.

Dog Dander (e5)

Nicholas, C. E., et al. (2011). Dog allergen levels in homes with hypoallergenic compared with nonhypoallergenic dogs. American Journal of Rhinology & Allergy, 25(4), 252–256.
Konieczny, A., Morgenstern, J. P., Bizinkauskas, C. B., et al. (1997). The major dog allergens, Can f 1 and Can f 2, are salivary lipocalin proteins: Cloning and immunological characterization of the recombinant forms. Immunology, 92(4), 577–586.
Apostolovic, D., Vidaurre, S. S., Curin, M., et al. (2016). The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1. Allergy, 71(10), 1490–1495.
Arbes, S. J., Cohn, R. D., Yin, M., et al. (2008). Dog allergen (Can f 1) and cat allergen (Fel d 1) in US homes: Results from the National Survey of Lead and Allergens in Housing. Annals of Allergy, Asthma & Immunology, 101(5), 517–523.

Mold

Mold Mix (mx1)

Bush, R. K., et al. (2006). The medical effects of mold exposure. Journal of Allergy and Clinical Immunology, 117(2), 326–333.
Simon-Nobbe, B., et al. (2008). The spectrum of fungal allergy. International Archives of Allergy and Immunology, 145(1), 58–86.
Latgé, J. P. (1999). Aspergillus fumigatus and aspergillosis. Clinical Microbiology Reviews, 12(2), 310–350.
Horner, W. E., et al. (1995). Air- and dustborne mycoflora in houses free of water damage and fungal growth. Applied and Environmental Microbiology, 61(9), 3238–3245.
Bush, R. K., & Portnoy, J. M. (2001). The role and abatement of fungal allergens in allergic diseases. Journal of Allergy and Clinical Immunology, 107(3), S430–S440.

House Dust

House Dust (h1)

Arlian, L. G., et al. (2002). House dust mite allergens: Ecology and distribution. Current Allergy and Asthma Reports, 2(5), 401–411.
Platts-Mills, T. A. E., et al. (1992). Dust mite allergens and asthma: Report of a second international workshop. Journal of Allergy and Clinical Immunology, 89(5), 1046–1060.
Arlian, L. G., & Platts-Mills, T. A. (2001). The biology of dust mites and the remediation of mite allergens in allergic disease. Journal of Allergy and Clinical Immunology, 107(3), S406–S413.

House Dust Mites Mix (dx2)

Platts-Mills, T. A. E., Vervloet, D., Thomas, W. R., et al. (1997). Dust mite allergens and asthma: A worldwide problem. Journal of Allergy and Clinical Immunology, 99(2), S231–S236.
Arlian, L. G. (1991). House-dust-mite allergens: A review. Experimental and Applied Acarology, 10(3–4), 167–186.
Arlian, L. G., Neal, J. S., & Morgan, M. S. (2002). Dust mite allergens: Ecology and distribution. Current Allergy and Asthma Reports, 2(5), 401–411

Insects

Cockroach - German (i6)

Rosenstreich, D. L., et al. (1997). The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma. New England Journal of Medicine, 336(19), 1356–1363.
Gore, J. C., & Schal, C. (2007). Cockroach allergen biology and mitigation in the indoor environment. Annual Review of Entomology, 52, 439–463.

Cockroach Mix (ix1)

Rosenstreich, D. L., et al. (1997). The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma. New England Journal of Medicine, 336(19), 1356–1363.
Gore, J. C., & Schal, C. (2007). Cockroach allergen biology and mitigation in the indoor environment. Annual Review of Entomology, 52, 439–463.

Bee Venom (i1)

Son, D. J., Lee, J. W., Lee, Y. H., et al. (2007). "Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds." Pharmacology & Therapeutics, 115(2), 246-270.
Golden, D. B. K. (2007). "Insect sting anaphylaxis." Immunology and Allergy Clinics of North America, 27(2), 261-272.
Biló, B. M., Rueff, F., Mosbech, H., et al. (2005). "Diagnosis of Hymenoptera venom allergy." Allergy, 60(12), 1339-1349.
Golden, D. B. K., Kelly, D., Hamilton, R. G., et al. (2009). "Venom immunotherapy reduces large local reactions to insect stings." Journal of Allergy and Clinical Immunology, 123(6), 1371-1375.

Dairy & eggs

Cow’s Milk (f199)

Fiocchi, A., Dahda, L., Dupont, C., et al. (2016). Cow’s milk allergy: Towards an update of DRACMA guidelines. World Allergy Organization Journal, 9(1), 35.
Venter, C., & Arshad, S. H. (2011). The epidemiology of food allergy. Pediatric Clinics of North America, 58(2), 327–349.
Savage, J. H., & Johns, C. B. (2015). Food allergy: Epidemiology and natural history. Immunology and Allergy Clinics of North America, 35(1), 45–59.

Egg White (f1)

Savage, J. H., & Johns, C. B. (2015). Food allergy: Epidemiology and natural history. Immunology and Allergy Clinics of North America, 35(1), 45–59.
Lemon-Mulé, H., Sampson, H. A., Sicherer, S. H., et al. (2008). Immunologic changes in children with egg allergy ingesting extensively heated egg. The Journal of Allergy and Clinical Immunology, 122(5), 977–983.
Mine, Y., & Yang, M. (2008). Recent advances in the understanding of egg allergens: Basic, industrial, and clinical perspectives. Journal of Agricultural and Food Chemistry, 56(13), 4874–4880.

Grains

Wheat (f4)

Sapone, A., et al. (2012). Spectrum of gluten-related disorders: consensus on new nomenclature and classification. BMC Medicine, 10, 13.
Sicherer, S. H., & Sampson, H. A. (2010). Food allergy. Journal of Allergy and Clinical Immunology, 125(2), S116–S125.
De Potter, M., Jones, M. P., Walker, M. M., et al. (2020). Incidence and prevalence of self-reported non-coeliac wheat sensitivity and gluten avoidance in Australia. Medical Journal of Australia, 212(3), 126–131.

Legumes

Peanut (f13)

Sicherer, S. H., & Sampson, H. A. (2007). Peanut allergy: emerging concepts and approaches for an apparent epidemic. The Journal of Allergy and Clinical Immunology, 120(3), 491–503.
Koppelman, S. J., Wensing, M., Ertmann, M., et al. (2004). Relevance of Ara h1, Ara h2 and Ara h3 in peanut-allergic patients, as determined by immunoglobulin E Western blotting, basophil-histamine release and intracutaneous testing: Ara h2 is the most important peanut allergen. Clinical and Experimental Allergy, 34(4), 583–590.

Soy (f14)

Savage, J. H., et al. (2010). The natural history of soy allergy. Journal of Allergy and Clinical Immunology, 125(3), 683–691.
Wilson, N., et al. (2005). Food Allergen Labeling and Consumer Protection Act (FALCPA): Guidelines for allergen labeling compliance. Journal of Food Science, 70(8), R126–R128.
Savage, J. H., & Johns, C. B. (2015). Food allergy: Epidemiology and natural history. Immunology and Allergy Clinics of North America, 35(1), 45–59.

Nuts

Almond (f20)

Sicherer, S. H., & Sampson, H. A. (2010). Food allergy. Journal of Allergy and Clinical Immunology, 125(2), S116–S125.
Sicherer, S. H., & Sampson, H. A. (2014). Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment. Journal of Allergy and Clinical Immunology, 133(2), 291–307.

Walnut (f256)

Villalta, D., Scala, E., Mistrello, G., et al. (2019). Evidence of cross-reactivity between different seed storage proteins from hazelnut (Corylus avellana) and walnut (Juglans regia) using recombinant allergen proteins. International Archives of Allergy and Immunology, 178(1), 89–92.
Teuber, S. S., & Sathe, S. K. (2004). Tree nut allergies. Current Allergy and Asthma Reports, 4(1), 47–53.

Hazelnut (f17)

Flinterman, A. E., Hoekstra, M. O., Meijer, Y., et al. (2006). Clinical reactivity to hazelnut in children: Association with sensitization to birch pollen or nuts? Journal of Allergy and Clinical Immunology, 118(5), 1186–1189.
Jeong, K., Lee, S.-Y., Ahn, K., et al. (2016). A multicenter study on anaphylaxis caused by peanut, tree nuts, and seeds in children and adolescents. Allergy, 72(1), 91–99.

Fruits

Apple (f49)

Lahti, A., Björksten, F., & Hannuksela, M. (1980). Allergy to birch pollen and apple, and cross-reactivity of the allergens studied with the RAST. Allergy, 35(4), 297-300.
Fernández-Rivas, M. (2003). Cross-reactivity between fruit and vegetables. Allergologia et Immunopathologia, 31(3), 141-146.

Tropical Fruits (fx166)

Lucas, J. S. A., Lewis, S. A., & Hourihane, J. O'B. (2003). Kiwi fruit allergy: a review. Pediatric Allergy and Immunology, 14(6), 420-428.
Sussman, G., Sussman, A., & Sussman, D. (2010). Oral allergy syndrome. Canadian Medical Association Journal, 182(11), 1210-1211.
Crespo, J. F., Rodríguez, J., & James, J. M. et al. (2002). Reactivity to potential cross-reactive foods in fruit-allergic patients: implications for prescribing food avoidance. Allergy, 57(10), 946-949.

Fruit Mix (fx153)

Sancho, A. I., Hoffmann-Sommergruber, K., Alessandri, S., et al. (2010). Authentication of food allergen quality by physicochemical and immunological methods. Clinical & Experimental Allergy, 40(7), 973-986.
Fernández-Rivas, M., Bolhaar, S., González-Mancebo, E., et al. (2006). Apple allergy across Europe: How allergen sensitization profiles determine the clinical expression of allergies to plant foods. Journal of Allergy and Clinical Immunology, 118(2), 481-488.
Blanco, C., Carrillo, T., Castillo, R., et al. (1994). Latex allergy: Clinical features and cross-reactivity with fruits. Annals of Allergy, 73(4), 309-314.
Brehler, R., Theissen, U., Mohr, C., & Luger, T. (1997). Latex-fruit syndrome: Frequency of cross-reacting IgE antibodies. Allergy, 52(4), 404-410.
Fernández-Rivas, M. (2003). Cross-reactivity between fruit and vegetables. Allergologia et Immunopathologia, 31(3), 141-146.
Paschke, A., Kinder, H., Zunker, K.,et al. (2001). Characterization of cross-reacting allergens in mango fruit. Allergy, 56(3), 237-242.

Seafood

Cod (f3)

Kuehn, A., et al. (2014). Fish allergens at a glance: Variable allergenicity of parvalbumins, the major fish allergens. Frontiers in Immunology, 5, 179.
Sharp, M. F., & Lopata, A. L. (2014). Fish allergy: In review. Clinical Reviews in Allergy & Immunology, 46(3), 258–271.
Kris-Etherton, P. M., et al. (2002). Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation, 106(21), 2747–2757.

Shrimp (f24)

Ayuso, R. (2011). "Update on the diagnosis and treatment of shellfish allergy." Current Allergy and Asthma Reports, 11(4), 309–316.
Ayuso, R., Reese, G., Leong-Kee, S., et al. (2002). "Molecular basis of arthropod cross-reactivity: IgE-binding cross-reactive epitopes of shrimp, house dust mite and cockroach tropomyosins." International Archives of Allergy and Immunology, 129(1), 38–48.

Fishmix (fx704)

Calder, P. C. (2013). Omega-3 polyunsaturated fatty acids and inflammatory processes: Nutrition or pharmacology? British Journal of Clinical Pharmacology, 75(3), 645-662.
Kris-Etherton, P. M., Harris, W. S., Appel, L. J., et al. (2002). Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation, 106(21), 2747-2757.
Simopoulos, A. P. (1991). Omega-3 fatty acids in health and disease and in growth and development. American Journal of Clinical Nutrition, 54(3), 438-463.
Sharp, M. F., & Lopata, A. L. (2014). Fish allergy: in review. Clinical Reviews in Allergy & Immunology, 46(3), 258-271.

Seafood Mix (fx722)

Kuehn, A., Swoboda, I., Arumugam, K., et al. (2014). Fish allergens at a glance: Variable allergenicity of parvalbumins, the major fish allergens. Frontiers in Immunology, 5, 179.
Ayuso, R., Grishina, G., Bardina, L., et al. (2011). Update on the diagnosis and treatment of shellfish allergy. Current Allergy and Asthma Reports, 11(1), 42-50.
Leung, P. S. C., Chow, W. K., Duffey, S., Kwan, H. S., Gershwin, M. E., & Chu, K. H. (1996). IgE reactivity against a cross-reactive allergen in crustacea and mollusca: Evidence for tropomyosin as the common allergen. Journal of Allergy and Clinical Immunology, 98(5), 954-961.
Lehrer, S. B., Ayuso, R., Reese, G. (2003). Seafood allergy and allergens: a review. Marine Biotechnology, 5(4), 339-348.

Shellfish Mix (fx272)

Ayuso, R. (2011). "Update on the diagnosis and treatment of shellfish allergy." Current Allergy and Asthma Reports, 11(4), 309-316.
Lopata, A. L. (2010). "Shellfish allergy." Clinical & Experimental Allergy, 40(6), 850-858.
Faber, M. A., Pascal, M., El Kharbouchi, O., et al. (2017). "Shellfish allergens: tropomyosin and beyond." Allergy, 72(6), 842-848.

Meat

Meat Mix (fx693)

Commins, S. P., & Platts-Mills, T. A. E. (2013). "Tick bites and red meat allergy." Current Opinion in Allergy and Clinical Immunology, 13(4), 354-359.
Wanniang, N., Kuehn, A., & Morisset, M. et al. (2022). Poultry meat allergy: A review of allergens and clinical phenotypes. Current Treatment Options in Allergy, 9 (2), 84-92.
Fiocchi, A., Restani, P., & Riva, E. et al. (1995). Meat allergy: I – Specific IgE to BSA and OSA in atopic, beef sensitive children. Journal of the American College of Nutrition, 14(3), 239-244.
Klug, C., Focke, M., & Hemmer, W. et al. (2013). Identification and characterization of meat allergens for improved diagnosis of meat allergy. Clinical and Translational Allergy, 3(Suppl 3), P174.
Epelboin, L., Roche, F., & Duyemes, M. et al. (2021). Allergy to mammalian meat linked to Alpha-Gal syndrome potentially after tick bite in the Amazon: A case series. The American Journal of Tropical Medicine and Hygiene, 105(5), 1396-1403.

Meat Mix (fx246)

Voltolini, S., Spigno, F., Cioè, A., et al. (2013). "Bovine Serum Albumin: a double allergy risk." European Annals of Allergy and Clinical Immunology, 45(4), 144-147.
Wilson, J. M., & Platts-Mills, T. A. E. (2019). "Red meat allergy in children and adults." Current Opinion in Allergy and Clinical Immunology, 19(3), 229-235.
Commins, S. P., & Platts-Mills, T. A. E. (2013). "Tick bites and red meat allergy." Current Opinion in Allergy and Clinical Immunology, 13(4), 354-359.

Vegetables

Tomato (f25)

Westphal, S., Kempf, W., Foetisch, K., et al. (2004). "Tomato profilin Lyc e 1: IgE cross-reactivity and allergenic potency." Allergy, 59(5), 526–532.
Vieths, S., Scheurer, S., Ballmer-Weber, B. (2002). "Current understanding of cross-reactivity of food allergens and pollen." Annals of the New York Academy of Sciences, 964, 47–68.
Sicherer, S. H., & Sampson, H. A. (2014). Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment. Journal of Allergy and Clinical Immunology, 133(2), 291-307.

Carrot (f31)

Ballmer-Weber, B. K., Wüthrich, B., & Wangorsch, A. et al. (2001). Carrot allergy: double-blinded, placebo-controlled food challenge and identification of allergens. Journal of Allergy and Clinical Immunology, 108(2), 301-307.
Ballmer-Weber, B. K., Wangorsch, A., & Bohle, B. et al. (2005). Component-resolved in vitro diagnosis in carrot allergy: Does the use of recombinant carrot allergens improve the reliability of the diagnostic procedure? Clinical and Experimental Allergy, 35(8), 970-976.

Potato (f35)

Seppälä, U., Majamaa, H., & Turjanmaa, K. et al. (2001). Identification of four novel potato (Solanum tuberosum) allergens belonging to the family of soybean trypsin inhibitors. Allergy, 56(7), 619-626.
Cox, A. L., Eigenmann, P. A., & Sicherer, S. H. (2021). Clinical relevance of cross-reactivity in food allergy. Journal of Allergy and Clinical Immunology: In Practice, 9(1), 82-99.

Celery (f85)

Ballmer-Weber, B. K., Vieths, S., Lüttkopf, D., et al. (2000). Celery allergy confirmed by double-blind, placebo-controlled food challenge: A clinical study in 32 subjects with a history of adverse reactions to celery root. Journal of Allergy and Clinical Immunology, 106(2), 373–378.
Savage, J. H., & Johns, C. B. (2015). Food allergy: epidemiology and natural history. Immunology and Allergy Clinics of North America, 35(1), 45–59.

Cross Reactive Carbohydrate Determinants (CCD)

Commins, S. P. (2015). Carbohydrates as allergens. Current Allergy and Asthma Reports, 15(1), 492.

Food Intolerance

Gluten Cereals

Shewry, P. R. (2009). Wheat. Journal of Experimental Botany, 60(6), 1537-1553.
Idehen, E., Tang, Y., & Sang, S. (2017). Bioactive phytochemicals in barley. Journal of Food and Drug Analysis, 25(1), 148-161.
Arendt, E. K., & Zannini, E. (2013). Rye and rye products. In Cereal Grains for the Food and Beverage Industries (pp. 296-319).
Whitehead, A., Beck, E. J., Tosh, S., et al. (2014). Cholesterol-lowering effects of oat β-glucan: a meta-analysis of randomized controlled trials. American Journal of Clinical Nutrition, 100(6), 1413-1421.
Fasano, A., & Catassi, C. (2012). Clinical practice. Celiac disease. New England Journal of Medicine, 367(25), 2419-2426.
Tye-Din, J. A., Galipeau, H. J., & Agardh, D. (2018). Celiac disease: a review of current concepts in pathogenesis, prevention, and novel therapies. Frontiers in Pediatrics, 6, 350.

Non-Gluten Cereals

Fabjan, N., Rode, J., Košir, I. J., et al. (2003). Tartary buckwheat (Fagopyrum tataricum Gaertn.) as a source of dietary rutin and quercitrin. Journal of Agricultural and Food Chemistry, 51(22), 6452-6455.
Rastogi, A., & Shukla, S. (2013). Amaranth: A new millennium crop of nutraceutical values. Critical Reviews in Food Science and Nutrition, 53(2), 109-125.
Repo-Carrasco-Valencia, R., Hellström, J. K., Pihlava, J. M., et al. (2010). Flavonoids and other phenolic compounds in Andean indigenous grains: Quinoa (Chenopodium quinoa), kaniwa (Chenopodium pallidicaule), and kiwicha (Amaranthus caudatus). Food Chemistry, 120(1), 128-133.
Adom, K. K., & Liu, R. H. (2002). Antioxidant activity of grains. Journal of Agricultural and Food Chemistry, 50(21), 6182-6187.
Frei, M., & Becker, K. (2003). Studies on the in vitro starch digestibility and the glycemic index of six different indigenous rice cultivars from the Philippines. Food Chemistry, 83(3), 395-402.

Egg

He, W., Li, X., & Zhang, W. (2020). Egg white proteins and their potential for controlling food allergy. Journal of Agricultural and Food Chemistry, 68(21), 5677-5688.
Samaranayaka, A., & Li-Chan, E. C. Y. (2008). Autolysis-assisted production of fish protein hydrolysates with antioxidant properties from Pacific hake (Merluccius productus). Food Chemistry, 107(2), 768-776.
Mine, Y., & Zhang, J. W. (2002). Comparative studies on antigenicity and allergenicity of native and denatured egg white proteins. Journal of Agricultural and Food Chemistry, 50(9), 2679-2683.
Cherian, G. (2011). Essential fatty acids and early life programming in meat animals. Advances in Food and Nutrition Research, 64, 191-209.

Milk

Muir, J. G., & Gibson, P. R. (2005). Dietary triggers of irritable bowel syndrome. Current Opinion in Gastroenterology, 21(2), 189-196.
Vesa, T. H., Marteau, P., & Korpela, R. (2000). Lactose intolerance. Journal of the American College of Nutrition, 19(2 Suppl), 165S-175S.
Ramsing, R., Santo, R., Kim, B. F., et al. (2023). Dairy and plant-based milks: Implications for nutrition and planetary health. Current Environmental Health Reports, 10(3), 291-302.
Docena, G. H., Fernandez, R., Chirdo, F. G., et al. (1996). Identification of casein as the major allergenic and antigenic protein of cow's milk. Allergy, 51(6), 412-416.
De Greef, E., Hauser, B., Devreker, T., et al. (2012). Diagnosis and management of cow’s milk protein allergy in infants. World Journal of Pediatrics, 8(1), 19-24.

Fish & Seafood

Sicherer, S. H., & Sampson, H. A. (2010). Food allergy. Journal of Allergy and Clinical Immunology, 125(2), S116-S125.
Ruxton, C. H. S., Reed, S. C., Simpson, M. J. A., & Millington, K. J. (2004). The health benefits of omega-3 polyunsaturated fatty acids: a review of the evidence. Journal of Human Nutrition and Dietetics, 17(5), 449-459.
Calder, P. C. (2013). Omega-3 polyunsaturated fatty acids and inflammatory processes. British Journal of Clinical Pharmacology, 75(3), 645-662.
Sicherer, S. H., & Sampson, H. A. (2014). Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment. Journal of Allergy and Clinical Immunology, 133(2), 291-307.
Khora, S. S. (2016). Seafood-associated shellfish allergy: A comprehensive review. Immunological Investigations, 45(6), 504-530.

Meat

Bender, D. A. (2012). Nutritional Biochemistry of the Vitamins. Cambridge University Press.
Institute of Medicine (US) Panel on Micronutrients. (2001). Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. National Academies Press (US).
Craig, W. J., & Mangels, A. R. (2009). Position of the American Dietetic Association: vegetarian diets. Journal of the American Dietetic Association, 109(7), 1266-1282.
Fraser, G. E. (2009). Vegetarian diets: what do we know of their effects on common chronic diseases? The American Journal of Clinical Nutrition, 89(5), 1607S-1612S.
Fairweather-Tait, S. J., Collings, R., & Hurst, R. (2010). Selenium bioavailability: current knowledge and future research requirements. The American Journal of Clinical Nutrition, 91(5), 1484S-1491S.

Vegetables

Slavin, J. L., & Lloyd, B. (2012). Health benefits of fruits and vegetables. Advances in Nutrition, 3(4), 506-516.
Steinmetz, K. A., & Potter, J. D. (1996). Vegetables, fruit, and cancer prevention: a review. Journal of the American Dietetic Association, 96(10), 1027-1039.
Kris-Etherton, P. M., Hecker, K. D., Bonanome, A., et al. (2002). Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. The American Journal of Medicine, 113(9), 71-88.
Liu, R. H. (2013). Health-promoting components of fruits and vegetables in the diet. Advances in Nutrition, 4(3), 384S-392S.
Dreher, M. L. (2018). Whole Fruits and Fruit Fiber Emerging Health Effects. Nutrients, 10(12), 1833.

Legumes

Sicherer, S. H., & Sampson, H. A. (2014). Food allergy: epidemiology, pathogenesis, diagnosis, and treatment. Journal of Allergy and Clinical Immunology, 133(2), 291-307.
Food Allergy Research & Education (FARE). (2021). Soy Allergy. www.foodallergy.org/living-food-allergies/food-allergy-essentials/common-allergens/soy
Bhatia, J., Greer, F., & American Academy of Pediatrics Committee on Nutrition. (2008). Use of soy protein-based formulas in infant feeding. Pediatrics, 121(5), 1062-1068.
National Institute of Allergy and Infectious Diseases (NIAID). (2011). Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary for Patients, Families, and Caregivers. U.S. Department of Health and Human Services.
EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA). (2014). Scientific Opinion on the evaluation of allergenic foods and food ingredients for labelling purposes. EFSA Journal, 12(11), 3894.

Fruits

Slavin, J. L., & Lloyd, B. (2012). Health benefits of fruits and vegetables. Advances in Nutrition, 3(4), 506-516.
Steinmetz, K. A., & Potter, J. D. (1996). Vegetables, fruit, and cancer prevention: a review. Journal of the American Dietetic Association, 96(10), 1027-1039.
Kris-Etherton, P. M., Hecker, K. D., Bonanome, A., et al. (2002). Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. The American Journal of Medicine, 113(9), 71-88.
Liu, R. H. (2013). Health-promoting components of fruits and vegetables in the diet. Advances in Nutrition, 4(3), 384S-392S.
Dreher, M. L. (2018). Whole fruits and fruit fiber: Emerging health effects. Nutrients, 10(12), 1833.

Nuts & Seeds

Ros, E. (2010). Nuts and cardiovascular disease: an overview. Current Opinion in Clinical Nutrition and Metabolic Care, 13(6), 659-663.
Sacks, F. M., Lichtenstein, A. H., Wu, J. H. Y., et al. (2017). Dietary fats and cardiovascular disease: A presidential advisory from the American Heart Association. Circulation, 136(3), e1-e23.
O'Keefe, A. W., De Schryver, S., Mill, J., et al. (2014). Diagnosis and management of food allergies: new and emerging options: a systematic review. Journal of Asthma and Allergy, 7, 141-164.
Fasano, A., & Catassi, C. (2012). Celiac disease. New England Journal of Medicine, 367(25), 2419-2426.
Thompson, T. (2003). Oats and the gluten-free diet. Journal of the American Dietetic Association, 103(3), 376-379.
Shewry, P. R., & Hey, S. J. (2015). The contribution of wheat to human diet and health. Food and Energy Security, 4(3), 178-202.
Jones, J. M. (2017). Wheat Belly: An Analysis of Selected Statements and Basic Theses from the Book. Cereal Foods World, 62(2), 78-86.
Truchliński, J., Sembratowicz, I., Gorzel, M., & Kiełtyka-Dadasiewicz, A. (2014). Allergenic potential of cosmetic ingredients. Archives of Physiotherapy and Global Researches, 18(1), 7-15.

Others

Ali, A., Shehzad, A., Khan, M. R., et al. (2012). Yeast, its types and role in fermentation during bread making process—A review. Pakistan Journal of Food Sciences, 22(3), 171-179.
Nieber, K. (2017). The impact of coffee on health. Planta Medica, 83(16), 1256-1263.
Higdon, J. V., & Frei, B. (2006). Coffee and health: a review of recent human research. Critical Reviews in Food Science and Nutrition, 46(2), 101-123.
Turnbull, J. L., Adams, H. N., & Gorard, D. A. (2015). Review article: The diagnosis and management of food allergy and food intolerances. Alimentary Pharmacology & Therapeutics, 41(1), 3-25.
Niggemann, B., & Beyer, K. (2005). Diagnostic pitfalls in food allergy in children. Allergy, 60(1), 104-107.
Sicherer, S. H., & Sampson, H. A. (2018). Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management. Journal of Allergy and Clinical Immunology, 141(1), 41-58.

Rotation diet plan

Brostoff, J., & Gamlin, L. (2000). The Complete Guide to Food Allergy and Intolerance. Bloomsbury Publishing.
Gibson, P. R., & Shepherd, S. J. (2010). Evidence-based dietary management of functional gastrointestinal symptoms: The FODMAP approach. Journal of Gastroenterology and Hepatology, 25(2), 252-258.
Turnbull, J. L., Adams, H. N., & Gorard, D. A. (2015). Review article: The diagnosis and management of food allergy and food intolerances. Alimentary Pharmacology & Therapeutics, 41(1), 3-25.
Drisko, J., Bischoff, B., Hall, M., & McCallum, R. (2006). Treating irritable bowel syndrome with a food elimination diet followed by food challenge and probiotics. Journal of the American College of Nutrition, 25(6), 514-522.
Lewis, S. K. (with Blakley, L. D.). Allergy & Candida Cooking—Rotational Style. Canary Connect Publications. Coralville, Iowa.

Privacy Policy

1. An overview of data protection

General information

The following information will provide you with an easy to navigate overview of what will happen with your personal data when you visit this website. The term “personal data” comprises all data that can be used to personally identify you. For detailed information about the subject matter of data protection, please consult our Data Protection Declaration, which we have included beneath this copy.

Data recording on this website

Who is the responsible party for the recording of data on this website (i.e., the “controller”)?

The data on this website is processed by the operator of the website, whose contact information is available under section “Information about the responsible party (referred to as the “controller” in the GDPR)” in this Privacy Policy.

How do we record your data?

We collect your data as a result of your sharing of your data with us. This may, for instance, be information you enter into our contact form. Other data shall be recorded by our IT systems automatically or after you consent to its recording during your website visit. This data comprises primarily technical information (e.g., web browser, operating system, or time the site was accessed). This information is recorded automatically when you access this website.

What are the purposes we use your data for?

A portion of the information is generated to guarantee the error free provision of the website. Other data may be used to analyze your user patterns. If contracts can be concluded or initiated via the website, the transmitted data will also be processed for contract offers, orders or other order enquiries.

What rights do you have as far as your information is concerned?

You have the right to receive information about the source, recipients, and purposes of your archived personal data at any time without having to pay a fee for such disclosures. You also have the right to demand that your data are rectified or eradicated. If you have consented to data processing, you have the option to revoke this consent at any time, which shall affect all future data processing. Moreover, you have the right to demand that the processing of your data be restricted under certain circumstances. Furthermore, you have the right to log a complaint with the competent supervising agency. Please do not hesitate to contact us at any time if you have questions about this or any other data protection related issues.

2. Hosting

We are hosting the content of our website at the following provider: Hetzner

The provider is the Hetzner Online GmbH, Industriestr. 25, 91710 Gunzenhausen, Germany (hereinafter referred to as Hetzner). For details, please view the data privacy policy of Hetzner: https://www.hetzner.com/de/legal/privacy-policy/. We use Hetzner on the basis of Art. 6(1)(f) GDPR. We have a legitimate interest in the most reliable depiction of our website possible. If appropriate consent has been obtained, the processing is carried out exclusively on the basis of Art. 6(1)(a) GDPR and § 25 (1) TDDDG, insofar the consent includes the storage of cookies or the access to information in the user’s end device (e.g., device fingerprinting) within the meaning of the TDDDG. This consent can be revoked at any time.

Data processing

We have concluded a data processing agreement (DPA) for the use of the above-mentioned service. This is a contract mandated by data privacy laws that guarantees that they process personal data of our website visitors only based on our instructions and in compliance with the GDPR.

3. General information and mandatory information

Data protection

The operators of this website and its pages take the protection of your personal data very seriously. Hence, we handle your personal data as confidential information and in compliance with the statutory data protection regulations and this Data Protection Declaration. Whenever you use this website, a variety of personal information will be collected. Personal data comprises data that can be used to personally identify you. This Data Protection Declaration explains which data we collect as well as the purposes we use this data for. It also explains how, and for which purpose the information is collected. We herewith advise you that the transmission of data via the Internet (i.e., through e-mail communications) may be prone to security gaps. It is not possible to completely protect data against third-party access.

Information about the responsible party (referred to as the “controller” in the GDPR)

The data processing controller on this website is:

AESKU.DIAGNOSTICS GmbH & Co. KG

Vertreten durch Dr. Torsten Matthias

Mikroforum Ring 2, 55234 Wendelsheim, Deutschland

Phone: +49 6734 96220

E-mail: aeskucare@aesku.com

The controller is the natural person or legal entity that single-handedly or jointly with others makes decisions as to the purposes of and resources for the processing of personal data (e.g., names, e-mail addresses, etc.).

Storage duration

Unless a more specific storage period has been specified in this privacy policy, your personal data will remain with us until the purpose for which it was collected no longer applies. If you assert a justified request for deletion or revoke your consent to data processing, your data will be deleted, unless we have other legally permissible reasons for storing your personal data (e.g., tax or commercial law retention periods); in the latter case, the deletion will take place after these reasons cease to apply.

General information on the legal basis for the data processing on this website

If you have consented to data processing, we process your personal data on the basis of Art. 6(1)(a) GDPR or Art. 9 (2)(a) GDPR, if special categories of data are processed according to Art. 9 (1) DSGVO. In the case of explicit consent to the transfer of personal data to third countries, the data processing is also based on Art. 49 (1)(a) GDPR. If you have consented to the storage of cookies or to the access to information in your end device (e.g., via device fingerprinting), the data processing is additionally based on § 25 (1) TDDDG. The consent can be revoked at any time. If your data is required for the fulfillment of a contract or for the implementation of pre-contractual measures, we process your data on the basis of Art. 6(1)(b) GDPR. Furthermore, if your data is required for the fulfillment of a legal obligation, we process it on the basis of Art. 6(1)(c) GDPR. Furthermore, the data processing may be carried out on the basis of our legitimate interest according to Art. 6(1)(f) GDPR. Information on the relevant legal basis in each individual case is provided in the following paragraphs of this privacy policy.

Designation of a data protection officer

We have appointed a data protection officer.

DSBOK GmbH

Oliver Krause

Untergasse 2

65474 Bischofsheim

Phone: 06144402197

E-mail: aesku@dsbok.de

Recipients of personal data

In the scope of our business activities, we cooperate with various external parties. In some cases, this also requires the transfer of personal data to these external parties. We only disclose personal data to external parties if this is required as part of the fulfillment of a contract, if we are legally obligated to do so (e.g., disclosure of data to tax authorities), if we have a legitimate interest in the disclosure pursuant to Art. 6 (1)(f) GDPR, or if another legal basis permits the disclosure of this data. When using processors, we only disclose personal data of our customers on the basis of a valid contract on data processing. In the case of joint processing, a joint processing agreement is concluded.

Revocation of your consent to the processing of data

A wide range of data processing transactions are possible only subject to your express consent. You can also revoke at any time any consent you have already given us. This shall be without prejudice to the lawfulness of any data collection that occurred prior to your revocation.

Right to object to the collection of data in special cases; right to object to direct advertising (Art. 21 GDPR)

IN THE EVENT THAT DATA ARE PROCESSED ON THE BASIS OF ART. 6(1)(E) OR (F) GDPR, YOU HAVE THE RIGHT TO AT ANY TIME OBJECT TO THE PROCESSING OF YOUR PERSONAL DATA BASED ON GROUNDS ARISING FROM YOUR UNIQUE SITUATION. THIS ALSO APPLIES TO ANY PROFILING BASED ON THESE PROVISIONS. TO DETERMINE THE LEGAL BASIS, ON WHICH ANY PROCESSING OF DATA IS BASED, PLEASE CONSULT THIS DATA PROTECTION DECLARATION. IF YOU LOG AN OBJECTION, WE WILL NO LONGER PROCESS YOUR AFFECTED PERSONAL DATA, UNLESS WE ARE IN A POSITION TO PRESENT COMPELLING PROTECTION WORTHY GROUNDS FOR THE PROCESSING OF YOUR DATA, THAT OUTWEIGH YOUR INTERESTS, RIGHTS AND FREEDOMS OR IF THE PURPOSE OF THE PROCESSING IS THE CLAIMING, EXERCISING OR DEFENCE OF LEGAL ENTITLEMENTS (OBJECTION PURSUANT TO ART. 21(1) GDPR). IF YOUR PERSONAL DATA IS BEING PROCESSED IN ORDER TO ENGAGE IN DIRECT ADVERTISING,

YOU HAVE THE RIGHT TO OBJECT TO THE PROCESSING OF YOUR AFFECTED PERSONAL DATA FOR THE PURPOSES OF SUCH ADVERTISING AT ANY TIME. THIS ALSO APPLIES TO PROFILING TO THE EXTENT THAT IT IS AFFILIATED WITH SUCH DIRECT ADVERTISING. IF YOU OBJECT, YOUR PERSONAL DATA WILL SUBSEQUENTLY NO LONGER BE USED FOR DIRECT ADVERTISING PURPOSES (OBJECTION PURSUANT TO ART. 21(2) GDPR).

Right to log a complaint with the competent supervisory agency

In the event of violations of the GDPR, data subjects are entitled to log a complaint with a supervisory agency, in particular in the member state where they usually maintain their domicile, place of work or at the place where the alleged violation occurred. The right to log a complaint is in effect regardless of any other administrative or court proceedings available as legal recourse.

Right to data portability

You have the right to have data that we process automatically on the basis of your consent or in fulfillment of a contract handed over to you or to a third party in a common, machine-readable format. If you demand the direct transfer of the data to another controller, this will be done only if it is technically feasible.

Information about, rectification and eradication of data

Within the scope of the applicable statutory provisions, you have the right to demand information about your archived personal data, their source and recipients as well as the purpose of the processing of your data at any time. You may also have a right to have your data rectified or eradicated. If you have questions about this subject matter or any other questions about personal data, please do not hesitate to contact us at any time.

Right to demand processing restrictions

You have the right to demand the imposition of restrictions as far as the processing of your personal data is concerned. To do so, you may contact us at any time. The right to demand restriction of processing applies in the following cases: In the event that you should dispute the correctness of your data archived by us, we will usually need some time to verify this claim. During the time that this investigation is ongoing, you have the right to demand that we restrict the processing of your personal data.

If the processing of your personal data was/is conducted in an unlawful manner, you have the option to demand the restriction of the processing of your data instead of demanding the eradication of this data. If we do not need your personal data any longer and you need it to exercise, defend or claim legal entitlements, you have the right to demand the restriction of the processing of your personal data instead of its eradication. If you have raised an objection pursuant to Art. 21(1) GDPR, your rights and our rights will have to be weighed against each other. As long as it has not been determined whose interests prevail, you have the right to demand a restriction of the processing of your personal data.

If you have restricted the processing of your personal data, these data – with the exception of their archiving –may be processed only subject to your consent or to claim, exercise or defend legal entitlements or to protect the rights of other natural persons or legal entities or for important public interest reasons cited by the European Union or a member state of the EU.

SSL and/or TLS encryption

For security reasons and to protect the transmission of confidential content, such as purchase orders or inquiries you submit to us as the website operator, this website uses either an SSL or a TLS encryption program. You can recognize an encrypted connection by checking whether the address line of the browser switches from “http://” to “https://” and also by the appearance of the lock icon in the browser line. If the SSL or TLS encryption is activated, data you transmit to us cannot be read by third parties.

Rejection of unsolicited e-mails

We herewith object to the use of contact information published in conjunction with the mandatory information to be provided in our Site Notice to send us promotional and information material that we have not expressly requested. The operators of this website and its pages reserve the express right to take legal action in the event of the unsolicited sending of promotional information, for instance via SPAM messages.

4. Recording of data on this website

Cookies

Our websites and pages use what the industry refers to as “cookies.” Cookies are small data packages that do not cause any damage to your device. They are either stored temporarily for the duration of a session (session cookies) or they are permanently archived on your device (permanent cookies). Session cookies are automatically deleted once you terminate your visit. Permanent cookies remain archived on your device until you actively delete them, or they are automatically eradicated by your web browser. Cookies can be issued by us (first-party cookies) or by third-party companies (so-called third-party cookies). Third-party cookies enable the integration of certain services of third-party companies into websites (e.g., cookies for handling payment services). Cookies have a variety of functions. Many cookies are technically essential since certain website functions would not work in the absence of these cookies (e.g., the shopping cart function or the display of videos). Other cookies may be used to analyze user behavior or for promotional purposes. Cookies, which are required for the performance of electronic communication transactions, for the provision of certain functions you want to use (e.g., for the shopping cart function) or those that are necessary for the optimization (required cookies) of the website (e.g., cookies that provide measurable insights into the web audience), shall be stored on the basis of Art. 6(1)(f) GDPR, unless a different legal basis is cited.

The operator of the website has a legitimate interest in the storage of required cookies to ensure the technically error-free and optimized provision of the operator’s services. If your consent to the storage of the cookies and similar recognition technologies has been requested, the processing occurs exclusively on the basis of the consent obtained (Art. 6(1)(a) GDPR and § 25 (1) TDDDG); this consent may be revoked at any time. You have the option to set up your browser in such a manner that you will be notified any time cookies are placed and to permit the acceptance of cookies only in specific cases. You may also exclude the acceptance of cookies in certain cases or in general or activate the delete-function for the automatic eradication of cookies when the browser closes. If cookies are deactivated, the functions of this website may be limited. Which cookies and services are used on this website can be found in this privacy policy.

Consent with Cookiebot

Our website uses consent technology from Cookiebot to obtain your consent to the storage of certain cookies on your end device or for the use of certain technologies and to document this in a data protectioncompliant manner. The provider of this technology is Cybot A/S, Havnegade 39, 1058 Copenhagen, Denmark (hereinafter “Cookiebot”). When you enter our website, a connection is established with the Cookiebot servers to obtain your consent and provide you with other explanations regarding the use of cookies. Cookiebot will then store a cookie in your browser to identify the consent you have given or its revocation. The data collected in this way is stored until you request us to delete it, delete the Cookiebot cookie itself or the purpose for which the data is stored no longer applies. Mandatory legal storage obligations remain unaffected. Cookiebot is used to obtain the legally required consent for the use of cookies. The legal basis for this is Art. 6(1)(c) GDPR.

Data processing

Server log files

The provider of this website and its pages automatically collects and stores information in so-called server log files, which your browser communicates to us automatically. The information comprises: The type and version of browser used

• The used operating system

• Referrer URL

• The hostname of the accessing computer

• The time of the server inquiry

• The IP address

This data is not merged with other data sources.

This data is recorded on the basis of Art. 6(1)(f) GDPR. The operator of the website has a legitimate interest in the technically error free depiction and the optimization of the operator’s website. In order to achieve this, server log files must be recorded.

Request by e-mail, telephone, or fax

If you contact us by e-mail, telephone or fax, your request, including all resulting personal data (name, request) will be stored and processed by us for the purpose of processing your request. We do not pass these data on without your consent. These data are processed on the basis of Art. 6(1)(b) GDPR if your inquiry is related to the fulfillment of a contract or is required for the performance of pre-contractual measures.

In all other cases, the data are processed on the basis of our legitimate interest in the effective handling of inquiries submitted to us (Art. 6(1)(f) GDPR) or on the basis of your consent (Art. 6(1)(a) GDPR) if it has been obtained; the consent can be revoked at any time. The data sent by you to us via contact requests remain with us until you request us to delete, revoke your consent to the storage or the purpose for the data storage lapses (e.g. after completion of your request). Mandatory statutory provisions - in particular statutory retention periods - remain unaffected.

Registration on this website

You have the option to register on this website to be able to use additional website functions. We shall use the data you enter only for the purpose of using the respective offer or service you have registered for. The required information we request at the time of registration must be entered in full. Otherwise, we shall reject the registration. To notify you of any important changes to the scope of our portfolio or in the event of technical modifications, we shall use the e-mail address provided during the registration process. The data entered during registration is processed for the purpose of implementing the user relationship established by the registration and, if necessary, for the initiation of further contracts (Art. 6 (1)(b) GDPR). The data recorded during the registration process shall be stored by us as long as you are registered on this website. Subsequently, such data shall be deleted. This shall be without prejudice to mandatory statutory retention obligations.

5. Plug-ins and Tools

Google Fonts (local embedding)

This website uses so-called Google Fonts provided by Google to ensure the uniform use of fonts on this site. These Google fonts are locally installed so that a connection to Google’s servers will not be established in conjunction with this application.

For more information on Google Fonts, please follow this link: https://developers.google.com/fonts/faq and consult Google’s Data Privacy Declaration under: https://policies.google.com/privacy?hl=en.

6. Use of the Portal and Processing of Healthcare Data

Our website allows healthcare professionals who have purchased AESKUCARE® Food Intolerance, AESKUCARE® Allergy, or AESKUCARE® Gluten Related Disorders Point-of-Care tests to upload test results and create structured reports. These reports visually present test results and include additional information and contextual details.

Purchase and Use of AESKUCARE Tests

The AESKUCARE® test can only be purchased and conducted by healthcare professionals. All necessary instructions for performing the test are included in the test kit itself. The AESKU.CARE Portal serves as an optional add-on and is not part of the test kit itself.

Processed Data

Registration data of healthcare professionals: Name, email address, and professional information. Uploaded test results: Test data is uploaded anonymously. Each test is associated with a specific LOT number. It is the sole responsibility of the healthcare professional to determine whether the test number is linked to a real individual.

Anonymity of Test Data

All test data uploaded to the portal is anonymous, identified only by a specific LOT number. The healthcare professional retains full control over whether the test number is linked to a real person. The responsibility for maintaining and protecting the data and ensuring compliance with applicable privacy laws lies entirely with the healthcare professional.

Storage

Test results of end customers are not stored on the portal. After creating the report, it is neither archived nor saved. Healthcare professionals can download the generated report or send it directly to their end customers.